Section Chief, Cardiac Surgery
Director, Libin Cardiovascular Institute of Alberta Clinical and Academic Department Head, Cardiac Sciences Professor, University of Calgary
P:403-944-1033 F:403-944-1592 Assistant: Shannon Perry shannon.perry@albertahealthservices Room C849 Foothills Medical Centre 1403 29th Street NW Calgary AB T2N 2T9
Todd Anderson is a clinician scientist at the University of Calgary in the Department of Medicine. His current research interests are in the evaluation and treatment of endothelial dysfunction in humans. He obtained his MD degree at the University of Calgary and then undertook residency training in Internal Medicine, Cardiology and Interventional Cardiology in Calgary. He pursued further research training in coronary physiology at the Brigham and Women's Hospital at Harvard Medical School. He returned to the University of Calgary and has been on staff since 1995. He is currently a Professor of Medicine and a Scholar of the Alberta Heritage Foundation for Medical Research. His research interests include the assessment of coronary physiology and peripheral endothelial function in subjects with atherosclerosis or its risk factors. He is funded by the Alberta Heritage Foundation for Medical Research, the Alberta Heart and Stroke Foundation, the Canadian Institutes of Health, the Canadian Diabetes Association. He also holds numerous physician initiated industry grants. His clinical interest is percutaneous coronary intervention.
Endothelial function in the coronary circulation and the peripheral vasculature -mechanisms of diabetic endothelial dysfunction in animal and human models -the effect of modulation of endothelial derived NO on endothelial function in patients with diabetes, and in a separate study, chronic renal failure -the interaction between CRP and endothelial function -the long-term prognostic significance of endothelial function as a determinant of cardiovascular outcomes -the effect of novel anti-lipidemic drugs on endothelial function and atherosclerosis regression
Selected Publications Chugh SK, Koppel J, Scott M, Shewchuk L, Bonan R, Tardif J-C,. Coronary flow velocity reserve does not correlate with TIMI Frame Count in patients undergoing non-emergency percutaenous coronary intervention. J Am Coll Cardiol. 44:778-782. (2004) Verma S, Wang C-H, Lonn E, Charbonneau F, Buithieu J, Title LM,. C-reactive protein poorly correlates with brachial endothelial function.. European Heart Journal. 25:1754-60. (2004) Anderson TJ, Worthley M, Goodhart DM, Curtis MJ. Basal Coronary Nitric Oxide Activity is Not Related to the Burden of Atherosclerosis: An Intravascular Ultrasound Study. Am J Cardiol. 95:1170-74. (2005) Worthley M, Charbonneau F, Anderson TJ. Commentary on Impaired Flow-Mediated Dilation and Risk of Restenosis in Patients Undergoing Coronary Stent Implantation. Nature Clinical Practice Cardiovascular Medicine. 2:238-239. (2005) Yan RT, Anderson TJ, Charbonneau F, Title L, Verma S, Lonn EM. Relationship Between Carotid Artery Intima-Media Thickness and Brachial Artery Flow-Mediated Dilation in Middle-Aged Healthy Men. J Am Coll Cardiol. 45:1980-86. (2005) Verma S, Wang C-H, Li S-H, Lonn EM, Charbonneau F, Title L, Anderson TJ, for the FATE Investigators. The relationship between soluble CD40L and Framingham coronary heart disease risk in healthy subjects. Atherosclerosis. 182:361-365. (2005) Pannirselvam M, Wiehler B, Anderson TJ, Triggle CR. Enhanced vascular reactivity of small mesenteric arteries from diabetic mice is associated with enhanced oxidative stress and cyclooxygenase products. BJP. 144:953. (2005)